Big 12 Football Predictions: Our Insiders Predict Week Two Matchups
Sep 3, 2025, 2:58 PM | Updated: 2:59 pm
Iowa State hosts Iowa in a rivalry game. That's among the highlight matchups in Big 12 football for week two of the season. (Photo by Matthew Holst/Getty Images)
(Photo by Matthew Holst/Getty Images)
SALT LAKE CITY – We’re starting to get into the guts of Big 12 football in 2025.
There are some marquee non-conference matchups in this week’s slate.
Daily podcasts on BYU and Utah football. 📺🏈
🔵: Cougar Tracks | @Mitch_Harper
🟥: The Utah Blockcast | @BartleKSLsports pic.twitter.com/3RSHeSQfZl— KSL Sports (@kslsports) September 3, 2025
Here are our weekly insider picks from BYU Insider Mitch Harper and Utah Insider Steve Bartle.
Check out their daily podcasts, Cougar Tracks, and The Utah Blockcast, for the latest on the Cougs and the Utes.
Big 12 Standings Entering Week 2
- Iowa State – 1-0 in the Big 12 (2-0 overall)
- Kansas – 0-0 (2-0)
- Arizona – 0-0 (1-0)
- Arizona State – 0-0 (1-0)
- BYU – 0-0 (1-0)
- UCF – 0-0 (1-0)
- Houston – 0-0 (1-0)
- Oklahoma State – 0-0 (1-0)
- TCU – 0-0 (1-0)
- Texas Tech – 0-0 (1-0)
- Utah – 0-0 (1-0)
- West Virginia – 0-0 (1-0)
- Baylor – 0-0 (0-1)
- Cincinnati – 0-0 (0-1)
- Colorado – 0-0 (0-1)
- Kansas State – 0-1 (1-1 overall)
Season Totals
(Through Week 1)
- Steve Bartle: 16-2
- Mitch Harper: 15-3
Big 12 football teams ranked in the AP Top 25 poll entering Week 2
- 12. Arizona State
- 16. Iowa State
- 24. Texas Tech
- 25. Utah
Big 12 football predictions throughout the 2025 season
Week 0 | Week 1 | Week 2 | Week 3 | Week 4 | Week 5 | Week 6 | Week 7 | Week 8 | Week 9 | Week 10 | Week 11 | Week 12 | Week 13 | Week 14
No. 16 Iowa State vs. Iowa
- Saturday, September 6
- Kickoff: 10 a.m. (MDT)/11 a.m. (CDT)
- TV: FOX
Insider Predictions
- Steve Bartle: Iowa State
- Mitch Harper: Iowa State
I believe Iowa State pulls out the victory in the Cy-Hawk rivalry. Rocco Becht has been playing some really good football, and the balance ISU has on offense will be the difference in this one. -Bartle
Iowa State hasn’t defeated Iowa in Ames since 2011. However, the Cyclones have won two of the last three in the series. Like last year, the first one to 20 wins this game. Give me Iowa State. -Harper
Baylor at No. 17 SMU
- Saturday, September 6
- Kickoff: 10 a.m. (MDT)/11 a.m. (CDT)
- TV: The CW
Insider Predictions
- Steve Bartle: Baylor
- Mitch Harper: SMU
This is an important one for Baylor. If they don’t get this one, does Dave Aranda land on the hot seat again? I think Baylor will win, but it will be tough. Auburn highlighted a major sore spot with its lack of size along the defensive front. -Bartle
The injury to defensive lineman Jackie Marshall feels significant for Baylor. SMU is an offensive juggernaut on the hilltop. The Ponies send Baylor to a 0-2 start on the season. -Harper
No. 24 Texas Tech vs. Kent State
- Saturday, September 6
- Kickoff: 10 a.m. (MDT)/11 a.m. (CDT)
- TV: TNT/truTV/HBO Max
Insider Predictions
- Steve Bartle: Texas Tech
- Mitch Harper: Texas Tech
Wreck ‘Em, but it will be interesting to see how the Red Raiders manage without Behren Morton… potentially. -Bartle
Congrats to Kent State for beating Merrimack to end a 21-game losing streak; the good vibes will be short-lived as Tech rolls. Wreck ’em. -Harper
Oklahoma State at No. 6 Oregon
- Saturday, September 6
- Kickoff: 1:30 p.m. (MDT)/12:30 p.m. (PDT)
- TV: CBS
Insider Predictions
- Steve Bartle: Oregon
- Mitch Harper: Oregon
Hauss Hejny’s injury is a tough blow for the Cowboys, but Oregon is rolling through Gundy’s squad regardless. -Bartle
Why is Mike Gundy complaining about scheduling non-conference opponents based on budgets? It sounds like he is trying to make an excuse in advance for the beatdown Oregon is about to give the Pokes. -Harper
Kansas at Missouri
- Saturday, September 6
- Kickoff: 1:30 p.m. (MDT)/2:30 p.m. (CDT)
- TV: ESPN2
Insider Predictions
- Steve Bartle: Kansas
- Mitch Harper: Missouri
A big test for Jalon Daniels and the Jayhawks. If they pass this one, it’s officially time to put the Jayhawks in the conversation of contenders. Hopefully, Jayhawks fans will travel on the road to this one. My brain says Missouri, but I’m going to run it with Daniels and the Jayhawks in a wild one. -Bartle
I’m happy to see the Border War is back after a 14-year hiatus. If Kansas wins this one, do we begin to take them more seriously as a Big 12 title contender? Missouri has questions at quarterback with Sam Horn out with an injury. I’m giving an edge to the home team and going with Mizzou, but this one is coming down to the wire. -Harper
Cincinnati vs. Bowling Green
- Saturday, September 6
- Kickoff: 1:30 p.m. (MDT)/3:30 p.m. (EDT)
- TV/Stream: ESPN+
Insider Predictions
- Steve Bartle: Cincinnati
- Mitch Harper: Cincinnati
Brendan Sorsby couldn’t get it done in the clutch against Nebraska, but he and the Bearcats bounce back this week. -Bartle
Despite the loss last week, Cincy proved they have upgraded the talent significantly this year. Still waiting for the talented receivers to go off; they were missing last week in Kansas City.
Colorado vs. Delaware
- Saturday, September 6
- Kickoff: 1:30 p.m. (MDT)
- TV: FOX
Insider Predictions
- Steve Bartle: Colorado
- Mitch Harper: Colorado
Just when I buy into the Buffs, they let me down. Colorado only managing to score one touchdown on three 1st quarter takeaways is alarming. They should handle the Fightin’ Blue Hens, though. -Bartle
Colorado is a lot tougher on defense this year than they were in Coach Prime’s first two years. This team will surprise in the Big 12 this year, and they will cruise through the newest FBS member, Delaware, this weekend. -Harper
West Virginia vs. Ohio
- Saturday, September 6
- Kickoff: 2 p.m. (MDT)/4 p.m. (EDT)
- TV: ESPNU
Insider Predictions
- Steve Bartle: Ohio
- Mitch Harper: West Virginia
After getting the win at home, I’m a little worried for the Mountaineers on the road this week, especially with the Backyard Brawl on the horizon. Ohio played Rutgers pretty tight on the road last week. Parker Navarro is a veteran quarterback, and I think he leads the Bobcats to a win. -Bartle
Iowa State from two years ago can speak to the tricky nature of playing in Athens, Ohio. Which always begs the question, why are Big 12 teams still playing at MAC programs? There’s no upside. Still, I’m rolling with Rich Rod’s squad and I’ll call for Jaheim White to have a big game on the ground. -Harper
No. 25 Utah vs. Cal Poly
- Saturday, September 6
- Kickoff: 4 p.m. (MDT)
- TV/Stream: ESPN+
Insider Predictions
- Steve Bartle: Utah
- Mitch Harper: Utah
Utes roll. -Bartle
I’ll be surprised if we see any Utah starters in the second half. -Harper
Kansas State vs. Army
- Saturday, September 6
- Kickoff: 5 p.m. (MDT)/6 p.m. (CDT)
- TV: ESPN
Insider Predictions
- Steve Bartle: K-State
- Mitch Harper: K-State
Kansas State what is you doin’? This should be a comfortable win for the Wildcats, but I thought last week would be that too. The vibes are off in Manhattan; there needs to be a reset of some sort this week. -Bartle
If K-State lost this game to an Army squad that dropped a game against an FCS opponent last week, I can only imagine the knee-jerk reactions Wildcat fans will have towards Chris Klieman. They don’t have to worry, I’ll call for K-State’s defense to have a bounce-back performance and Avery Johnson to continue playing at a high level despite the criticisms. -Harper
Houston vs. Rice
- Saturday, September 6
- Kickoff: 5 p.m. (MDT)/6 p.m. (CDT)
- TV/Stream: ESPN+
Insider Predictions
- Steve Bartle: Houston
- Mitch Harper: Houston
This is one that Houston should win comfortably. -Bartle
The battle for the Bayou Bucket goes to the Coogs. -Harper
UCF vs. North Carolina A&T
- Saturday, September 6
- Kickoff: 5 p.m. (MDT)/7 p.m. (EDT)
- TV/Stream: ESPN+
Insider Predictions
- Steve Bartle: UCF
- Mitch Harper: UCF
Maybe a slightly better showing in week two for Scott Frost’s squad? But maybe not? Last week played out exactly how I felt it would; I just don’t know about Frost at the helm. This week should be better, though. -Bartle
Starting quarterback Cam Fancher suffered an injury in week one, leading to Tayven Jackson pulling off a week one win. Just grind out wins; they will do that again this week. -Harper
No. 12 Arizona State vs. Mississippi State
- Saturday, September 6
- Kickoff: 5:30 p.m. (MDT)/6:30 p.m. (CDT)
- TV: ESPN2
Insider Predictions
- Steve Bartle: Arizona State
- Mitch Harper: Arizona State
Despite the struggles last week, I think the Sun Devils come out sharp against the Bulldogs. This will be a tough test on the road, but Sam Leavitt and Jordyn Tyson are clearly synced up. -Bartle
Arizona State rolls past Mississippi State. The Sun Devils flex their toughness in SEC Country. -Harper
Arizona vs. Weber State
- Saturday, September 6
- Kickoff: 8 p.m. (MDT)/7 p.m. (MST)
- TV/Stream: ESPN+
Insider Predictions
- Steve Bartle: Arizona
- Mitch Harper: Arizona
The Wildcats take care of business this weekend…. Arizona, that is. -Bartle
I liked what I saw from Seth Doege’s offense last week. I’d expect to see more this week against Weber State. -Harper
BYU vs. Stanford
- Saturday, September 6
- Kickoff: 8:15 p.m. (MDT)
- TV: ESPN
- Radio: KSL NewsRadio (102.7 FM, 1160 AM)
Insider Predictions
- Steve Bartle: BYU
- Mitch Harper: BYU
Cougs roll. -Bartle
BYU wins this one. Two keys for BYU here are getting off the field on third down. The Cardinal lacks explosive playmaking ability through the air. Stop the run and get off the field. Then, on offense, protect former Stanford quarterback Bear Bachmeier. Stanford has nothing to lose in this game. They are going to bring some new wrinkles after a bye week. But this BYU team is tough, and Provo will overwhelm Stanford. BYU, big. -Harper
Mitch Harper is a BYU Insider for sports.ksl.com and hosts the Cougar Tracks Podcast daily on KSL Sports YouTube and KSL NewsRadio (SUBSCRIBE). Harper also co-hosts Cougar Sports Saturday (12–3 p.m.) on KSL NewsRadio.
Follow Mitch’s coverage of BYU athletics in the Big 12 Conference on X (formerly Twitter) and Instagram: @Mitch_Harper.
Steve Bartle is the Utah insider for KSL Sports. He hosts The Utah Blockcast (SUBSCRIBE) and appears on KSL Sports Zone to break down the Utes. You can follow him on X for the latest Utah updates and game analysis.
